Document Detail


Postprandial oxidative stress: influence of sex and exercise training status.
MedLine Citation:
PMID:  19915509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An individual's sex and exercise training status may influence oxidative stress. No study has compared postprandial oxidative stress in exercise-trained and untrained men and women. PURPOSE: To compare oxidative stress biomarkers and triglycerides (TAG) in 16 trained and 16 untrained men and women after ingestion of a high-fat meal. METHODS: Blood samples were collected before, and at 1, 2, 4, and 6 h after intake of a high-fat meal and analyzed for Trolox-equivalent antioxidant capacity (TEAC), malondialdehyde, hydrogen peroxide, xanthine oxidase activity, protein carbonyls (PC), and TAG. Area under the curve was calculated for each variable. RESULTS: Sex main effects were noted for all variables (P < 0.01), except for PC and TEAC (P > 0.05), with higher values for men compared with women. A training status main effect was noted for TEAC (P = 0.02), with higher values for trained compared with untrained subjects. No interaction effects were noted (P > 0.05). Regression analysis indicated that TAG explained the greatest degree of variability for oxidative stress variables, and premeal TAG best predicted the TAG response to feeding (R(2) = 0.50). CONCLUSIONS: With the exception of TEAC, for which higher values were noted for trained compared with untrained subjects, our findings indicate that sex, not exercise training status, influences postprandial oxidative stress. Specifically, women experience a significantly lower oxidative stress response to feeding compared with men. This seems mediated in part by the TAG response to feeding.
Authors:
Richard J Bloomer; David E Ferebee; Kelsey H Fisher-Wellman; John C Quindry; Brian K Schilling
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  41     ISSN:  1530-0315     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-20     Completed Date:  2010-02-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2111-9     Citation Subset:  IM; S    
Affiliation:
Department of Health and Sport Sciences, Cardiorespiratory/Metabolic Laboratory, University of Memphis, Memphis, TN 38152, USA. rbloomer@memphis.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Area Under Curve
Biochemical Phenomena
Biological Markers / blood
Dietary Fats / administration & dosage
Exercise / physiology*
Female
Humans
Male
Oxidative Stress / physiology*
Postprandial Period / physiology*
Sex Factors
Young Adult
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Dietary Fats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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