Document Detail


Postpartum psychosis with abnormal movements: dopamine supersensitivity unmasked by withdrawal of endogenous estrogens?
MedLine Citation:
PMID:  2211549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors describe two cases of postpartum psychosis accompanied by abnormal extrapyramidal movements. The presentation of these cases, as well as research evidence indicating that estrogens influence dopamine receptor function, leads the authors to hypothesize that dopamine receptor supersensitivity may have been induced by prepartum increases in endogenous estrogens and unmasked by postpartum estrogen withdrawal.
Authors:
S Vinogradov; J G Csernansky
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of clinical psychiatry     Volume:  51     ISSN:  0160-6689     ISO Abbreviation:  J Clin Psychiatry     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-11-01     Completed Date:  1990-11-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7801243     Medline TA:  J Clin Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  365-6     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Pacific Presbyterian Medical Center, San Francisco, CA 94115.
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MeSH Terms
Descriptor/Qualifier:
Adult
Basal Ganglia Diseases / physiopathology
Estrogens / adverse effects,  physiology*
Female
Humans
Movement Disorders / physiopathology*
Pregnancy
Psychotic Disorders / physiopathology*
Puerperal Disorders / physiopathology*
Receptors, Dopamine / physiology*
Substance Withdrawal Syndrome / etiology,  physiopathology
Up-Regulation*
Chemical
Reg. No./Substance:
0/Estrogens; 0/Receptors, Dopamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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