Document Detail

Postpartum optic neuritis: etiologic and pathophysiologic considerations.
MedLine Citation:
PMID:  10870918     Owner:  NLM     Status:  MEDLINE    
The clinical course of four patients with visual loss in the postpartum period due to acute optic neuritis is described. Factors that disclosed the underlying etiology and expression of disease are discussed. The clinical records of four women examined and managed for visual loss after uncomplicated pregnancies and term deliveries were reviewed. Neurodiagnostic examination, treatment modalities, and outcomes were assessed. These four women with varied and confounding medical histories, all with optic neuropathy, eventually were demonstrated to harbor demyelinating disease. Although visual loss in the postpartum period evokes differential diagnostic considerations, the authors' experience suggests that puerperal immune-mediated changes are responsible for activation of optic neuritis associated with relapsing multiple sclerosis.
H Leiba; J S Glaser; N J Schatz; R M Siatkowski
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society     Volume:  20     ISSN:  1070-8022     ISO Abbreviation:  J Neuroophthalmol     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-09-28     Completed Date:  2000-09-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9431308     Medline TA:  J Neuroophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  85-8     Citation Subset:  IM    
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Fort Lauderdale, Florida, USA.
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MeSH Terms
Brain / pathology
Glucocorticoids / therapeutic use
Magnetic Resonance Imaging
Methylprednisolone / therapeutic use
Multiple Sclerosis / complications*,  drug therapy,  physiopathology
Optic Neuritis / drug therapy,  etiology*,  physiopathology
Postpartum Period*
Prednisone / therapeutic use
Puerperal Disorders / drug therapy,  etiology*,  physiopathology
Vision Disorders / drug therapy,  etiology,  physiopathology
Visual Acuity
Reg. No./Substance:
0/Glucocorticoids; 53-03-2/Prednisone; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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