Document Detail

Postpartum myocardial infarction in a patient with antiphospholipid syndrome.
MedLine Citation:
PMID:  8155200     Owner:  NLM     Status:  MEDLINE    
Myocardial infarction in association with pregnancy in patients with the antiphospholipid syndrome has been reported once previously. Our patient, a 22-year-old multiparous woman, experienced a myocardial infarction in the postpartum period. She fulfilled the criteria for the diagnosis of the antiphospholipid syndrome (elevated anticardiolipin antibody levels, false-positive syphilis serology, history of deep vein thrombosis). Cardiac catheterization demonstrated appropriate central filling pressures, cardiac output of 7.14 L/min, and normal-appearing coronary arteries. She was treated with corticosteroids and indomethacin and recovered. Our article is relevant to clinical practice for the following reasons. First, it is the second time myocardial necrosis has been reported in a recently pregnant woman with the antiphospholipid syndrome. Second, the finding of normal-appearing coronary arteries at the time of catheterization lends credence to the hypothesis that either vasospasm or thrombosis are the inciting events. We speculate on the utility of various treatment regimens.
J M Thorp; N C Chescheir; B Fann
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  11     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1994 Jan 
Date Detail:
Created Date:  1994-05-19     Completed Date:  1994-05-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-3     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill 27514.
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MeSH Terms
Antibodies, Anticardiolipin / analysis*
Antiphospholipid Syndrome / complications*
Heart Catheterization
Myocardial Infarction / diagnosis,  immunology*
Pre-Eclampsia / immunology
Puerperal Disorders / diagnosis,  immunology*
Reg. No./Substance:
0/Antibodies, Anticardiolipin

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