Document Detail


Postpartum disappearance of chorionic gonadotropin from the maternal and neonatal circulations.
MedLine Citation:
PMID:  4061509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The disappearance of chorionic gonadotropin from the circulation was studied in a group of 10 healthy mothers and their offspring following vaginal delivery. Kinetic analysis revealed the following biexponential clearance characteristics: in mothers the rapid half-life component averaged 4.75 +/- 0.58 (SE) hours (n = 6), and the slow half-life component averaged 32.2 +/- 1.35 hours (n = 6); in neonates the respective overall means were 1.32 and 55.2 hours. Total elimination of chorionic gonadotropin (less than 0.005 IU/ml) occurred at a median time of 14 days following birth (range, 8 to 24 days) in mothers and at 1.5 days (range, 0 to 4 days) in neonates.
Authors:
F I Reyes; J S Winter; C Faiman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  153     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-12-06     Completed Date:  1985-12-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  486-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Chorionic Gonadotropin / blood*
Female
Fetal Blood
Half-Life
Humans
Infant, Newborn*
Labor, Obstetric
Male
Postpartum Period*
Pregnancy
Time Factors
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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