| Postorgasm illness syndrome--a spectrum of illnesses. | |
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MedLine Citation:
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PMID: 20214722 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: We describe two men with marked symptoms following orgasm. In each case, the symptoms were consistent with those found in postorgasm illness syndrome (POIS). AIM: Further elucidation of the cause of the patients' symptoms. METHODS: Both cases were investigated for causes of POIS with biochemical, hormonal, neurological, autonomic, cardiological, and psychological workup. RESULTS: Extensive investigation did not reveal a major organic cause for these patients' symptoms. Detailed history revealed likely differing etiologies in each case. In one case, the symptom picture suggested cytokine release, and, in fact, the patient subjectively improved by 80% on taking nonsteroidal anti-inflammatory drugs just prior to and for a day or two after orgasm. The other case appeared to have an ethnic/cultural etiology that was associated with the "Dhat" syndrome. CONCLUSION: The apparent differing etiologies/clinical associations of these cases highlight the need for careful history, examination, and investigations in patients presenting with POIS. We recommend that each case needs individual consideration and investigation, and treatment needs to be tailored to the likely cause. It seems likely that POIS represents a spectrum of syndromes of differing etiologies. Further research into the neurobiochemical sequelae of orgasm will be useful in understanding the pathological processes in these cases. |
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Authors:
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Jane Ashby; David Goldmeier |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-02-25 |
Journal Detail:
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Title: The journal of sexual medicine Volume: 7 ISSN: 1743-6109 ISO Abbreviation: J Sex Med Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-06-11 Completed Date: 2010-09-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101230693 Medline TA: J Sex Med Country: United States |
Other Details:
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Languages: eng Pagination: 1976-81 Citation Subset: IM |
Affiliation:
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Genitourinary Medicine/Human Immune deficiency Virus, Imperial College, St. Mary's Hospital, London, UK. jane.ashby@imperial.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Diagnosis, Differential Ejaculation* Fatigue / etiology* Homosexuality, Male Humans Male Mental Fatigue / etiology* Middle Aged Myofascial Pain Syndromes / etiology* Neurologic Examination Neuropsychological Tests Orgasm* Somatoform Disorders / etiology* Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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