Document Detail


Postoperative suppressive therapy for thyroid adenomas.
MedLine Citation:
PMID:  10966034     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thyroid adenoma is a common disease. If partial thyroidectomy is performed, postoperative suppression therapy is often given to avoid nodule development in the remaining thyroid. It is unclear whether this treatment is warranted. Patients who underwent a partial thyroidectomy with a histologic diagnosis of follicular thyroid adenoma from January 1985 until February 1998 were studied retrospectively. Patients were analyzed on the basis of postoperative therapy, new thyroid nodule growth, and costs. Seventy-six patients were identified with a recurrence rate of 4 per cent (3/76). Sixty-one per cent (46/76) were treated with postoperative thyroid suppression therapy, and no difference in new nodule development was noted with at least 6 months of follow-up (P = 0.274). No patients required reoperation. A large cost saving was shown for patients who were not treated with levothyroxine. We conclude that postoperative thyroid suppression may not be routinely indicated. A prospective, randomized study would be necessary to answer this question conclusively.
Authors:
R S Krouse; T McCarty; L M Weiss; L D Wagman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  66     ISSN:  0003-1348     ISO Abbreviation:  Am Surg     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-09-22     Completed Date:  2000-09-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  751-5     Citation Subset:  IM    
Affiliation:
Department of Surgery, City of Hope National Medical Center, Duarte, California 91010, USA.
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MeSH Terms
Descriptor/Qualifier:
Adenoma / surgery*
California
Cost Savings
Female
Humans
Male
Middle Aged
Retrospective Studies
Thyroid Neoplasms / surgery*
Thyroid Nodule / economics,  prevention & control*
Thyroidectomy*
Thyroxine / therapeutic use
Chemical
Reg. No./Substance:
7488-70-2/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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