Document Detail

Postoperative reduction of serum beta-HCG in testicular seminoma.
MedLine Citation:
PMID:  2456999     Owner:  NLM     Status:  MEDLINE    
Serum beta-HCG and urinary HCG were measured in 17 patients with histologically proved pure seminoma of the testis. The patients have been followed to date for 10 to 74 months after orchiectomy, and have no residual disease or recurrence of their disease. Preoperative urinary HCG levels were abnormal in 9 patients (53%). Serum beta-HCG levels were slightly elevated in 6 out of 12 patients evaluated, and were reduced after orchiectomy even in patients with preoperative normal beta-HCG levels (P less than 0.05). Preoperative levels of the tumour marker in seminoma were far lower than in patients with non-seminomatous germ cell tumours, but it would not be rare to see a small amount of HCG produced by the tumour cells in the seminoma.
S Sakashita; T Demura; T Gotoh; A Maru; T Koyanagi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International urology and nephrology     Volume:  20     ISSN:  0301-1623     ISO Abbreviation:  Int Urol Nephrol     Publication Date:  1988  
Date Detail:
Created Date:  1988-09-15     Completed Date:  1988-09-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0262521     Medline TA:  Int Urol Nephrol     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  281-6     Citation Subset:  IM    
Department of Urology, Hokkaido University School of Medicine, Sapporo, Japan.
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MeSH Terms
Chorionic Gonadotropin / blood*,  urine
Chorionic Gonadotropin, beta Subunit, Human
Dysgerminoma / blood,  pathology,  surgery*,  urine
False Positive Reactions
Middle Aged
Neoplasm Staging
Peptide Fragments / blood*,  urine
Postoperative Period
Testicular Neoplasms / blood,  pathology,  surgery*,  urine
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Peptide Fragments

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