Document Detail

Postoperative pain relief; a new approach: narcotics compared with non-steroidal anti-inflammatory drugs.
MedLine Citation:
PMID:  3056209     Owner:  NLM     Status:  MEDLINE    
The pain relief provided by regular intramuscular diclofenac and on demand intramuscular papaveretum was compared over a 48 h postoperative period in 114 patients undergoing total hip replacement. The study was of a randomised, single-blind, between-group design. Patients were assessed by a surgeon, physiotherapist and nursing staff. Diclofenac was more effective than papaveretum in pain control (P less than 0.001), wound tenderness (P less than 0.01), awareness (P less than 0.001) and mobilisation (P less than 0.01). Wound drainage (P greater than 0.05) and wound oedema (P greater than 0.05) were not significantly different in the two treatments. Gastrointestinal complications were encountered in both groups; two patients on diclofenac had to be withdrawn because of them. The use of diclofenac given as a postoperative analgesic is rewarding, particularly in patients undergoing musculoskeletal procedures. Patients will be more comfortable and will mobilise better during their whole postoperative course.
J M Buchanan; J Baldasera; P H Poole; J Halshaw; J K Dallard
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Annals of the Royal College of Surgeons of England     Volume:  70     ISSN:  0035-8843     ISO Abbreviation:  Ann R Coll Surg Engl     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-12-12     Completed Date:  1988-12-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7506860     Medline TA:  Ann R Coll Surg Engl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  332-5     Citation Subset:  IM    
Sunderland District General Hospital.
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MeSH Terms
Clinical Trials as Topic
Diclofenac / therapeutic use*
Hip Prosthesis
Middle Aged
Opium / therapeutic use*
Pain, Postoperative / drug therapy*
Random Allocation
Reg. No./Substance:
15307-86-5/Diclofenac; 8008-60-4/Opium
Comment In:
Ann R Coll Surg Engl. 1990 Jan;72(1):66   [PMID:  2137319 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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