Document Detail

Postoperative outcome of intracranial meningiomas; long-term prognosis.
MedLine Citation:
PMID:  7779743     Owner:  NLM     Status:  MEDLINE    
A retro- and prospective study was carried out in 150 patients who underwent surgery for benign (grade I) intracranial meningiomas (ICM). The mean duration of the follow-up was of 4 years. The subjects were divided into 4 groups according to the intervals of follow-up examination. The following variables were analysed: preoperative (clinical and paraclinical diagnosis), operative (macroscopic investigation) and postoperative (complications, sequelae, recurrences). The data were statistically processed. Conclusions are drawn concerning early results as well as predictors of long-term prognosis. Immediate improvement of the neurological and mental status was noted in 51% of patients. Late favourable outcome was found in only 35% of patients, demonstrating a tendency of late worsening. Postoperative morbidity includes complications (21%), sequelae (32%) and recurrence (22%). Predictor criteria in operated ICM patients are: onset type of illness, preoperative score, tumor location, edema and excessive vascularization of the brain as inspected at operation, early and late sequelae. Histological predictors for recurrence are: nuclear pleiomorphism, cellular mitoses, cell agglomerations. The frequency of recurrence, regardless of the operative technique, demonstrates the tendency toward malignancy of many of these tumors.
I Simoca; A A Olărescu; I Jipescu; M Lisievici
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Romanian journal of neurology and psychiatry = Revue roumaine de neurologie et psychiatrie     Volume:  32     ISSN:  1017-5644     ISO Abbreviation:  Rom J Neurol Psychiatry     Publication Date:    1994 Oct-Dec
Date Detail:
Created Date:  1995-07-19     Completed Date:  1995-07-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9014562     Medline TA:  Rom J Neurol Psychiatry     Country:  ROMANIA    
Other Details:
Languages:  eng     Pagination:  237-51     Citation Subset:  IM    
Clinic of Neurosurgery, G. Marinescu Hospital, Bucharest, Romania.
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MeSH Terms
Follow-Up Studies
Karnofsky Performance Status
Meningeal Neoplasms / pathology*,  surgery
Meningioma / pathology*,  surgery
Middle Aged
Neoplasm Recurrence, Local / epidemiology
Postoperative Complications / epidemiology
Prospective Studies
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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