Document Detail

Postoperative fatigue: a review.
MedLine Citation:
PMID:  19189174     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Postoperative fatigue (POF) significantly impacts well-being after major surgery. However, this topic has received little emphasis. METHODS: We conducted a comprehensive search on major databases with a focus on studies relevant to assessment and etiology of POF. RESULTS: POF has been measured by a number of different and inadequate instruments. It has a complicated etiology, with a number of biological and psychological factors implicated. However, the etiology of this condition has not been fully explained. CONCLUSIONS: The role of local inflammation in the development of POF requires further research. Multimodal interventions should be conducted with a focus on addressing various factors that contribute to the development and progression of POF.
Kamran Zargar-Shoshtari; Andrew G Hill
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  World journal of surgery     Volume:  33     ISSN:  0364-2313     ISO Abbreviation:  World J Surg     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-07-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704052     Medline TA:  World J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  738-45     Citation Subset:  IM    
Department of Surgery, University of Auckland, Middlemore Hospital, Auckland, New Zealand.
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MeSH Terms
Cytokines / blood
Fatigue / epidemiology*,  physiopathology,  psychology
Nutritional Status
Physical Fitness
Postoperative Complications / epidemiology*,  psychology
Postoperative Period
Vagus Nerve / physiopathology
Reg. No./Substance:
Comment In:
World J Surg. 2009 Apr;33(4):746-7   [PMID:  19199086 ]

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