Document Detail

Postoperative epidural analgesia in obese patients undergoing liver resection surgery.
MedLine Citation:
PMID:  23348160     Owner:  NLM     Status:  In-Data-Review    
Aim To investigate the relation of body mass index (BMI) with postoperative pain scores and volume of local anaesthetic (LA) administered epidurally in patients undergoing liver resection surgery. Methods Retrospective data from 167 patients who had epidural analgesia (EA) for liver resection surgery were analysed: 123 with BMI less 30kgm-2 and 44 with BMI more than 30kgm-2. Results Total volume of intraoperative bolus of epidural analgesia (EA) was not different between the BMI more than 30 kgm-2 and BMI less than 30 kgm-2 groups (p less 0.05). Mean rate of infusion (8.2±2.7 ml/h vs. 7.9±1.9 ml/h, p=0.0018), pain scores immediately after extubation of the trachea (0.91±0.9 vs. 0.55±0.7, p=0.017) and that before removal of epidural catheter (0.7±0.55 vs. 0.7±0.95, p=0.015) were higher in the BMI more than 30kgm-2 group when compared with the BMI ≤ 30kgm-2 group. However, there was no signiicant difference between the numbers of segments blocked. Conclusion The patients with BMI more than 30 kgm-2 undergoing liver resection experienced more postoperative pain on the day of surgery and before epidural catheter removal than patients with BMI less than 30 kgm-2, despite a higher rate of epidural infusion. Further studies are necessary to conirm these indings in order to determine adequate local anaesthetic dosing for thoracic epidural analgesia in obese patients.
Zoka Milan; Naresh Rajasekar; Sarah Hudson-Phillips; Heidi Pane; Henry Procter; Richard Simpson; Mitko Kocarev; Claire Biercamp; Mark Bellamy
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina     Volume:  10     ISSN:  1840-0132     ISO Abbreviation:  Med Glas Ljek komore Zenicko-doboj kantona     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101250177     Medline TA:  Med Glas Ljek komore Zenicko-doboj kantona     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  46-9     Citation Subset:  IM    
1Department of Anesthesia, St James's University Hospital, 2Leeds School of Medicine, Leeds, 3Harrogate District Hospital, Harrogate.
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