Document Detail


Postoperative endoscopic retrograde high dose-rate brachytherapy for cholangiocarcinoma.
MedLine Citation:
PMID:  11202795     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cholangiocarcinoma typically presents with disease unlikely to be completely resected, and prognosis remains poor. Improvements in imaging, endoscopy, and stenting have given rise to renewed interest in brachytherapy. Several recent retrospective series suggest a benefit to intraluminal brachytherapy, most commonly delivered by the transhepatic route. We describe a case in which brachytherapy was delivered via the nasobiliary route to address positive margins at the common bile duct stump. A custom catheter was manufactured to make the procedure feasible. Pertinent literature is reviewed, which supports the view that these malignancies benefit from high doses of radiation, if this can be achieved respecting normal tissue tolerance.
Authors:
R Ove; A Kennedy; P Darwin; O Haluszka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of clinical oncology     Volume:  23     ISSN:  0277-3732     ISO Abbreviation:  Am. J. Clin. Oncol.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-01-31     Completed Date:  2001-02-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8207754     Medline TA:  Am J Clin Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  559-61     Citation Subset:  IM    
Affiliation:
Department of Radiation Oncology, University of Maryland Medical System, Baltimore, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Bile Duct Neoplasms / radiotherapy*,  surgery
Bile Ducts, Intrahepatic
Brachytherapy* / methods
Catheterization
Cholangiocarcinoma / radiotherapy*,  surgery
Endoscopy
Humans
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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