| Postoperative controls in surgically treated hormonactive pituitary adenomas by use of magnetic resonance imaging. | |
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MedLine Citation:
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PMID: 3425409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The search of reliable imaging methods to detect the substrate for persisting hypersecretion in patients operated on for hormonactive pituitary adenoma prompted us to study the possibilities of the newly available Magnetic Resonance Imaging (MRI) technique in this regard. Pre- and postoperative MRI-studies where performed in 5 patients with persisting GH excess following transsphenoidal surgery as well as in 3 patients with micro- and 2 patients with macroprolactinomas. The MRI-findings were correlated with the results of the endocrinological examinations. Two acromegalic patients and three cases with microprolactinomas, who were successfully operated upon as defined by the functional criteria were also included to obtain a baseline for normal postoperative findings. The MRI-study was positive in all of the five patients with persisting GH-overproduction. In prolactinomas, the substrate of hypersecretion could only be detected, when the PRL-value exceeded 2,000 microU/ml. MRI may present an important diagnostic method for evaluating further treatment options in patients with remaining hormonal hypersecretion following transsphenoidal adenomectomy, particularly with regard to a second surgical approach. |
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Authors:
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R Oeckler; U Fink |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta neurochirurgica Volume: 88 ISSN: 0001-6268 ISO Abbreviation: Acta Neurochir (Wien) Publication Date: 1987 |
Date Detail:
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Created Date: 1988-02-23 Completed Date: 1988-02-23 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0151000 Medline TA: Acta Neurochir (Wien) Country: AUSTRIA |
Other Details:
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Languages: eng Pagination: 20-5 Citation Subset: IM |
Affiliation:
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Neurochirurgische Klinik der Ludwig-Maximilians-Universität München, Federal Republic of Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acromegaly
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etiology Adenoma / pathology, secretion, surgery* Adult Female Follow-Up Studies Growth Hormone / secretion Humans Magnetic Resonance Imaging Male Pituitary Neoplasms / pathology, secretion, surgery* Prolactin / secretion |
| Chemical | |
Reg. No./Substance:
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9002-62-4/Prolactin; 9002-72-6/Growth Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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