| Postoperative apnea in preterm infants. | |
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MedLine Citation:
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PMID: 3565813 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Preterm infants may become apneic during the immediate post-operative period. To define this risk, the authors studied prospectively the breathing patterns of 47 preterm infants less than 60 weeks postconception with pneumocardiograms before and after general inhalational anesthesia. Eighteen infants (37%) had prolonged apnea (greater than 15 s) postoperatively, and an additional seven infants (14%) had short apnea (6-15 s) postoperatively. An infant's risk of prolonged and short postoperative apnea was related to a young postconceptional age (P less than 0.05) and to a history of necrotizing enterocolitis (P less than 0.01). Furthermore, as the postconceptional age of the infant increased, the risk of postoperative apnea decreased proportionately (P less than 0.025). Among the 18 infants with prolonged apnea, 83% experienced multiple apneic episodes. Manual stimulation was required in order for breathing to return in 13 (72%) of the infants. Breathing resumed spontaneously in four (22%) of the infants, and one infant required mechanical ventilation due to repeated prolonged apnea. The first apneic event occurred within 2 h postoperatively in 13 of the infants (72%); the remaining five infants (28%) had their initial apneic episode as late as 12 h after operation. The postoperative time to the last prolonged apneic event was inversely related to the postconceptional age (P less than 0.01, r = -0.70) and extended up to 48 h postoperatively. The preoperative pneumocardiogram was not a reliable test for predicting postoperative apnea (sensitivity 56%, specificity 83%).(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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C D Kurth; A R Spitzer; A M Broennle; J J Downes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Anesthesiology Volume: 66 ISSN: 0003-3022 ISO Abbreviation: Anesthesiology Publication Date: 1987 Apr |
Date Detail:
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Created Date: 1987-04-30 Completed Date: 1987-04-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1300217 Medline TA: Anesthesiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 483-8 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia, Inhalation* Apnea / etiology* Gestational Age Humans Infant Infant, Newborn Infant, Premature* Postoperative Complications* Prospective Studies Risk |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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