Document Detail


Postoperative altered plasma growth hormone levels--a predictor for postoperative complications? A case report.
MedLine Citation:
PMID:  11759187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We compared the onset of predictors for postoperative complications (lactate, total T2 (tT2), total T4 (tT4) and cortisone) retrospectively with the onset of altered growth hormone (GH) concentration in a patient who had had a lethal postoperative outcome and in 13 patients who were without postoperative complications for a period of 24 hours postoperatively. Compared with the values of the patients without postoperative complications, GH values were elevated (68-fold) 1 h after surgery to 103 ng/ml and lactate was increased (12-fold) to 12.7 mmol/l at 6 h postoperatively in the patient with the lethal outcome. The other parameters measured (tT3, tT4 and cortisone) showed no rapid alteration during the first hours postoperatively. This case report suggests that the rapid postoperative onset of raised GH concentration in plasma may be an earlier marker for postoperative complications than the 'established' predictors.
Authors:
A Rümelin; G Nietgen; M Pirlich; P Thum; H J Schäfers; A von zur Mühlen; E Kirchner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Current medical research and opinion     Volume:  17     ISSN:  0300-7995     ISO Abbreviation:  Curr Med Res Opin     Publication Date:  2001  
Date Detail:
Created Date:  2001-12-10     Completed Date:  2002-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0351014     Medline TA:  Curr Med Res Opin     Country:  England    
Other Details:
Languages:  eng     Pagination:  88-92     Citation Subset:  IM    
Affiliation:
Medizinische Hochschule Hannover, Germany. ruemelin@mail.uni-mainz.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Aortic Valve / transplantation
Biological Markers / blood
Cortisone / blood
Heart Valve Diseases / surgery
Human Growth Hormone / blood*
Humans
Lactic Acid / blood
Male
Pilot Projects
Postoperative Complications / blood*
Predictive Value of Tests
Prospective Studies
Thyroid Hormones / blood
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Thyroid Hormones; 12629-01-5/Human Growth Hormone; 50-21-5/Lactic Acid; 53-06-5/Cortisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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