| Postoperative Residual Neuromuscular Blockade Is Associated with Impaired Clinical Recovery. | |
| | |
MedLine Citation:
|
PMID: 23337416 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND:In this investigation, we sought to determine the association between objective evidence of residual neuromuscular blockade (train-of-four [TOF] ratio <0.9) and the type, incidence, and severity of subjective symptoms of muscle weakness in the postanesthesia care unit (PACU).METHODS:TOF ratios of 149 patients were quantified with acceleromyography on arrival to the PACU. Patients were stratified into 2 cohorts: a TOF <0.9 group (n = 48) or a TOF ≥0.9 (control) group (n = 101). A standardized examination determined the presence or absence of 16 symptoms and 11 signs of muscle weakness on arrival to the PACU and 20, 40, and 60 minutes after admission.RESULTS:The incidence of symptoms of muscle weakness was significantly higher in the TOF <0.9 group at all times (P < 0.001), as was the median (range) number of symptoms from PACU arrival (7 [3-6] TOF <0.9 group vs 2 [0-11] control group; difference 5, 99% confidence interval of the difference 4-6) until 60 minutes after admission (2 [0-12] TOF <0.9 group vs 0 [0-11] control group; difference 2, 99% confidence interval of the difference 1-2) (all P < 0.0001).CONCLUSION:The incidence and severity of symptoms of muscle weakness were increased in the PACU in patients with a TOF <0.9. |
| | |
Authors:
|
Glenn S Murphy; Joseph W Szokol; Michael J Avram; Steven B Greenberg; Torin Shear; Jeffery S Vender; Jayla Gray; Elizabeth Landry |
Related Documents
:
|
17697816 - Intravascular ultrasound parameters associated with stent thrombosis after drug-eluting... 9822086 - Angiographic and clinical outcome following coronary stenting of small vessels: a compa... 23508336 - Long-term impacts of different posterior operations on curvature, neurological recovery... 16596526 - Functional vascular access evaluation after elective intervention for stenosis. 9845146 - Video-assisted thoracoscopic pericardial fenestration for loculated or recurrent effusi... 23222416 - Renoprotective effects of mineralocorticoid receptor blockers in patients with proteinu... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-21 |
Journal Detail:
|
Title: Anesthesia and analgesia Volume: - ISSN: 1526-7598 ISO Abbreviation: Anesth. Analg. Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-22 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
From the Department of Anesthesiology, NorthShore University HealthSystem, Evanston, Illinois. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Impact of Postoperative Nausea and Vomiting Prophylaxis with Dexamethasone on Postoperative Woun...
Next Document: The Antinociceptive and Antihyperalgesic Effects of Topical Propofol on Dorsal Horn Neurons in the R...