| Postoperative PTH measurement facilitates day 1 discharge after total thyroidectomy. | |
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MedLine Citation:
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PMID: 18573120 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: A new protocol for postoperative calcium management was developed with the aim of achieving an increase in the proportion of patients being safely discharged on the first postoperative day. We present our experience with the first 50 patients treated under this new protocol. PATIENTS AND DESIGN: A cohort study was performed involving the first 50 patients admitted for total or completion thyroidectomy, those data were then compared with a control group. Intact PTH (iPTH) was measured at 4-h postoperatively and patients with iPTH in the normal range were discharged on the first postoperative day. RESULTS: Mean age and sex distribution were similar in both groups. Mean lowest postoperative corrected calcium levels in the study group were 2.19 mmol/l and 2.15 mmol/l in the control group (P = 0.24). Parathyroid auto-transplantation was associated with low PTH levels (risk ratio = 0.49). Over 50% of patients (n = 27) were successfully discharged on the first postoperative day in the study group and no patient required readmission. Length of stay was significantly shorter in the study group, mean 1.64 vs. 2.20 days (P < 0.05). CONCLUSION: The use of iPTH accurately predicts hypocalcaemia after total thyroidectomy and can be used to facilitate safe early discharge for patients. |
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Authors:
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Simon Grodski; Catharina Ihre Lundgren; Stan Sidhu; Mark Sywak; Leigh Delbridge |
Publication Detail:
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Type: Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Clinical endocrinology Volume: 70 ISSN: 1365-2265 ISO Abbreviation: Clin. Endocrinol. (Oxf) Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-11 Completed Date: 2009-08-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346653 Medline TA: Clin Endocrinol (Oxf) Country: England |
Other Details:
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Languages: eng Pagination: 322-5 Citation Subset: IM |
Affiliation:
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Endocrine Surgical Unit, University of Sydney, Sydney, Australia. grodski@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calcium
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blood Cohort Studies Female Humans Hypocalcemia / blood, diagnosis*, etiology* Immunoassay / methods* Length of Stay Male Middle Aged Parathyroid Hormone / blood* Patient Discharge* Postoperative Period Predictive Value of Tests Thyroidectomy / adverse effects* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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