Document Detail

Postocclusive reactive hyperemia in healthy volunteers and patients with peripheral vascular disease measured by three noninvasive methods.
MedLine Citation:
PMID:  14562764     Owner:  NLM     Status:  MEDLINE    
Postocclusive reactive hyperemia (PORH) was evaluated in three healthy volunteers and in three patients with different etiologies and suffering from peripheral arterial occlusive disease (PAOD). Three noninvasive methods were used: transcutaneous oximetry (TcPO2), near-infrared spectroscopy (NIRS), and laser Doppler flowmetry (LDF). Changes in perfusion and oxygenation of tissue were measured on foot before, during, and after arterial occlusion on thigh. Numerical parameters were derived from measured signals for quantification of the PORH response. Results of all three methods provided distinction between healthy volunteers and patients. The experimental optical techniques of NIRS and LDF demonstrated more clearly than the well-established TcPO2 method the difference between healthy volunteers and patients. The dynamics of the PORH response proved to be a better indicator of peripheral vascular disorder than the amplitude of responses.
Tomaz Jarm; Rudi Kragelj; Adam Liebert; Piotr Lukasiewitz; Tatjana Erjavec; Marjeta Preseren-Strukelj; Roman Maniewski; Pavle Poredos; Damijan Miklavcic
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  530     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  2003  
Date Detail:
Created Date:  2003-10-17     Completed Date:  2003-11-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  661-9     Citation Subset:  IM    
University of Ljubljana, Faculty of Electrical Engineering, Trzaska 25, SI-1000 Ljubljana, Slovenia.
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MeSH Terms
Arterial Occlusive Diseases / complications*
Case-Control Studies
Hyperemia / complications*
Laser-Doppler Flowmetry
Peripheral Vascular Diseases / complications*
Reference Values
Spectroscopy, Near-Infrared

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