Document Detail


Postnatal retinal vascularization in former preterm infants with retinopathy of prematurity.
MedLine Citation:
PMID:  8127576     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To study the postnatally vascularized retina in former preterm infants in whom retinopathy of prematurity (ROP) stages 2 to 4a developed and spontaneously regressed. METHODS: Matched fundus photographs and fluorescein angiograms of the temporal peripheral retinas of 133 eyes (72 patients) were obtained after 2 years of age (mean, 7.7 years; range, 2-16.2 years) and were quantified by two masked observers with respect to the following parameters: (1) macular ectopia (in disc diameters); (2) vessel traction (in 30 degrees sectors); (3) radial length of postnatally vascularized retina (in disc diameters); and (4) capillary scaffolding of postnatally vascularized retina (as a density). These cicatricial outcomes were then compared with their active worst ROP stage. RESULTS: Of the 133 retinal montages, the following active worst ROP stages had been documented: 30 with stage 2, 42 with stage 3 mild, 32 with stage 3 moderate, 20 with stage 3 severe, and 9 with stage 4a. As active worst ROP stage increased, macular ectopia and vessel traction increased, and radial length and capillary scaffolding of postnatal retinal vascularization decreased. Retinal holes were documented frequently in eyes with high myopia. CONCLUSIONS: The peripheral retina in former preterm infants warrants close scrutiny for possible late rhegmatogenous retinal detachments. Prolonged retinal traction (by remnant shunt and extraretinal fibrovascular proliferation) between stable, posterior, prenatally vascularized retina, and unstable, postnatally vascularized retina may lead to the development of retinal holes characteristically located in the fragile, anterior, undifferentiated, nonvascularized retina.
Authors:
H A Mintz-Hittner; F L Kretzer
Related Documents :
18784936 - Stanford university network for diagnosis of retinopathy of prematurity (sundrop): 18-m...
19929096 - Video recording study of infants undergoing primary cheiloplasty: are arm restraints re...
3236156 - Surgical management of the cleft sternum.
16173516 - Cleft lip and palate in western slovakia in the years 1985-2000.
20843526 - The need for quality improvement in sweat testing infants after newborn screening for c...
19100266 - Personality and congenital adrenal hyperplasia: possible effects of prenatal androgen e...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Ophthalmology     Volume:  101     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-04-14     Completed Date:  1994-04-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  548-58     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Baylor College of Medicine, Houston 77030.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Female
Fluorescein Angiography
Fundus Oculi
Humans
Infant, Newborn
Infant, Premature
Male
Remission, Spontaneous
Retinal Vessels / pathology*,  physiology
Retinopathy of Prematurity / pathology*,  physiopathology
Grant Support
ID/Acronym/Agency:
EY02520/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The retinal venous pulse. Its relation to optic disc characteristics and choroidal pulse.
Next Document:  Ocular and optic nerve hemorrhages in abused infants with intracranial injuries.