Document Detail

Postnatal nutrition in extremely low birth weight infants and its impact on growth until the age of six years.
MedLine Citation:
PMID:  24127881     Owner:  NLM     Status:  Publisher    
AIM: To examine the impact of postnatal nutrition on long-term growth in extremely low birth weight infants.
METHOD: Retrospective analysis of postnatal nutrition and observational study of growth in 52 ELBW infants until the age of six.
RESULTS: Changes (Δ) of weight and length standard deviation scores (SDS) between birth to term correlated with protein-intake (rw =0.36; p=0.009; rL =0.35; p=0.01), whereas ΔHC correlated with lipid intake (rHC =0.38; p=0.005). Analysis of various intervals (0-2; 3-5; 6-8; 9-11 weeks) only showed significant impact on growth for energy (r=0.3; p<0.05) and lipids (r=0.23; p<0.05) at six to eight weeks. No significant correlations were found between postnatal nutritional parameters and long-term growth. However, postnatal growth restraint was negatively associated with length SDS (r=-3.34; p=0.015) and body mass index SDS (r=-3.34; p=0.018) at the age of six. Infants with postnatal growth restraint (n=25) caught up more in length (+1.78 SDS) than in weight (+0.43 SDS) whereas small for gestational age infants (n=8) caught up more in weight (+1.35 SDS) than in length (+1.07 SDS). This difference remained significant at the age of six.
CONCLUSION: Although no direct association between postnatal nutrition and long-term growth was found, weight at discharge was a strong predictor for long-term growth. This article is protected by copyright. All rights reserved.
Annika Peiler; Joachim Woelfle; Sonja Stutte; Felix Schreiner; Peter Bartmann; Bettina Gohlke
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-10-15
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-10-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
Paediatric Endocrinology Division, Children's Hospital, University of Bonn, Germany.
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