Document Detail

Postnatal changes in the distribution of lipid droplets within the liver lobule of the mouse.
MedLine Citation:
PMID:  227825     Owner:  NLM     Status:  MEDLINE    
The changes in the distribution of lipid droplets in the liver lobule were studied during the postnatal development of the mouse. At birth, and 1 day after birth, lipid droplets were evenly distributed throughout the lobule. A slightly uneven distribution of the droplets, more in centrilobular areas, appeared 2 days after birth. After this the difference in the number of droplets between the cells of the centrilobular and periportal areas became progressively more marked reaching a maximum by 17 days of age, and then decreasing to the adult level between 21 and 24 days. Thus, heterogeneity among hepatocytes with respect to lipid content is not present in newborn mice but develops gradually during the postnatal development.
M Asada; S Kanamura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of anatomy     Volume:  129     ISSN:  0021-8782     ISO Abbreviation:  J. Anat.     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1980-01-28     Completed Date:  1980-01-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0137162     Medline TA:  J Anat     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  423-6     Citation Subset:  IM    
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MeSH Terms
Animals, Newborn
Inclusion Bodies / metabolism*
Lipid Metabolism
Liver / cytology,  growth & development,  metabolism

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