| Postmortem validation of imaging-derived formulas for prediction of fetal lung volume. | |
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MedLine Citation:
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PMID: 12913348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the validity of existing imaging-derived formulas for predicting the fetal lung volume (FLV). METHODS: In a consecutive series of postmortem lungs without pulmonary anomalies, the observed FLV (FLV(obs)) after inflation was correlated with individual fetal variables used in imaging-derived formulas. In addition, FLV(obs) was correlated with the predicted FLV calculated according to these same formulas. RESULTS: Postmortem FLV(obs) showed a strong correlation with estimated fetal body weight, biparietal diameter, and head circumference (r > 0.9). The correlation of FLV(obs) with gestational age, femur length, and liver weight was less strong (0.8 < r < 0.9). The correlation was strongest for midgestation fetuses (between 22 and 32 weeks' gestation). The predicted FLV calculated using formulas based on fetal body weight, biparietal diameter, and head circumference showed the strongest correlation with the actual FLV(obs) (r > 0.9). CONCLUSIONS: Postmortem FLV(obs) strongly correlates with fetal body weight, biparietal diameter, and head circumference, especially in midgestation fetuses. Regression formulas based on these fetal variables provide the most accurate prediction of FLV. |
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Authors:
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Monique E De Paepe; Stephen R Carr; John A Cassese |
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Publication Detail:
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Type: Journal Article; Validation Studies |
Journal Detail:
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Title: Fetal diagnosis and therapy Volume: 18 ISSN: 1015-3837 ISO Abbreviation: Fetal. Diagn. Ther. Publication Date: 2003 Sep-Oct |
Date Detail:
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Created Date: 2003-08-12 Completed Date: 2003-12-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: Switzerland |
Other Details:
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Languages: eng Pagination: 353-9 Citation Subset: IM |
Copyright Information:
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Copyright 2003 S. Karger AG, Basel |
Affiliation:
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Department of Pathology, Women and Infants Hospital, Providence, RI 02905, USA. mdepaepe@wihri.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Body Weight Female Fetal Diseases / mortality, ultrasonography* Fetal Organ Maturity* Gestational Age Head / anatomy & histology Humans Infant, Newborn Lung / abnormalities*, ultrasonography Lung Volume Measurements* Predictive Value of Tests Pregnancy Reproducibility of Results Ultrasonography, Prenatal / standards* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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