Document Detail

Postmortem diagnostics of assumed food anaphylaxis in an unexpected death.
MedLine Citation:
PMID:  20193993     Owner:  NLM     Status:  MEDLINE    
Diagnosis of lethal anaphylaxis is known to be difficult to establish in forensic autopsy. Cases of anaphylactic shock have to be dealt with in forensic medicine comparatively frequently as death due to anaphylaxis is likely to occur rapidly and without warning in seemingly healthy subjects. Autopsy findings might hint at allergic reaction, but classic manifestations can also be completely absent. A case of suspected food anaphylaxis in a middle-aged woman is presented. The deceased had been known to suffer from multiple allergies. Death came about after an evening meal with friends. Dyspnoea was reported to have been followed by collapse, unconsciousness and death within minutes. The course of further analysis undertaken (toxicology, biochemistry, immunohistochemistry) is examplarily described. By means of the results presented we discuss problems and possibilities of postmortem diagnostics of food induced anaphylaxis.
S Unkrig; L Hagemeier; B Madea
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-03-02
Journal Detail:
Title:  Forensic science international     Volume:  198     ISSN:  1872-6283     ISO Abbreviation:  Forensic Sci. Int.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902034     Medline TA:  Forensic Sci Int     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  e1-4     Citation Subset:  IM    
Institute of Forensic Medicine, University of Bonn, Germany.
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MeSH Terms
Anaphylaxis / diagnosis*,  etiology
Antibodies / blood
Cell Degranulation
Death, Sudden / etiology*
Dyspnea / etiology
Food Hypersensitivity / complications,  diagnosis*
Forensic Pathology
Immunoglobulin E / immunology
Lung / pathology
Mast Cells / pathology
Middle Aged
Pharynx / pathology
Staining and Labeling
Tryptases / blood
Reg. No./Substance:
0/Antibodies; 37341-29-0/Immunoglobulin E; EC

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