| Postmortem diagnostics of assumed food anaphylaxis in an unexpected death. | |
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MedLine Citation:
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PMID: 20193993 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diagnosis of lethal anaphylaxis is known to be difficult to establish in forensic autopsy. Cases of anaphylactic shock have to be dealt with in forensic medicine comparatively frequently as death due to anaphylaxis is likely to occur rapidly and without warning in seemingly healthy subjects. Autopsy findings might hint at allergic reaction, but classic manifestations can also be completely absent. A case of suspected food anaphylaxis in a middle-aged woman is presented. The deceased had been known to suffer from multiple allergies. Death came about after an evening meal with friends. Dyspnoea was reported to have been followed by collapse, unconsciousness and death within minutes. The course of further analysis undertaken (toxicology, biochemistry, immunohistochemistry) is examplarily described. By means of the results presented we discuss problems and possibilities of postmortem diagnostics of food induced anaphylaxis. |
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Authors:
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S Unkrig; L Hagemeier; B Madea |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-03-02 |
Journal Detail:
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Title: Forensic science international Volume: 198 ISSN: 1872-6283 ISO Abbreviation: Forensic Sci. Int. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-26 Completed Date: 2010-08-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7902034 Medline TA: Forensic Sci Int Country: Ireland |
Other Details:
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Languages: eng Pagination: e1-4 Citation Subset: IM |
Affiliation:
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Institute of Forensic Medicine, University of Bonn, Germany. Susanne.unkrig@uni-bonn.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anaphylaxis
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diagnosis*,
etiology Antibodies / blood Cell Degranulation Death, Sudden / etiology* Dyspnea / etiology Female Food Hypersensitivity / complications, diagnosis* Forensic Pathology Humans Immunoglobulin E / immunology Lung / pathology Mast Cells / pathology Middle Aged Pharynx / pathology Staining and Labeling Tryptases / blood |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 37341-29-0/Immunoglobulin E; EC 3.4.21.59/Tryptases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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