Document Detail

Postinjection nonvasomotor reactions during chrysotherapy. Constitutional and rheumatic symptoms following injections of gold salts.
MedLine Citation:
PMID:  409414     Owner:  NLM     Status:  MEDLINE    
During gold sodium thiomalate (GST) therapy, 15% of 100 unselected patients described recurring postinjection reactions (PIRs), consisting of transient stiffness, arthralgias, myalgias, and constitutional symptoms. Six patients with more severe reactions requested discontinuation of chrysotherapy and for these, gold thioglucose (GTG) substitution abolished or amelioriated the reactions. The major significance of the PIR is that it may be a frequent cause of unwarranted premature abandonment of chrysotherapy.
J T Halla; J G Hardin; J E Linn
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  20     ISSN:  0004-3591     ISO Abbreviation:  Arthritis Rheum.     Publication Date:    1977 Jul-Aug
Date Detail:
Created Date:  1977-10-14     Completed Date:  1977-10-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1188-91     Citation Subset:  AIM; IM    
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MeSH Terms
Arthritis, Rheumatoid / drug therapy*
Gold Sodium Thiomalate / administration & dosage,  adverse effects*,  therapeutic use
Injections / adverse effects
Middle Aged
Reg. No./Substance:
12244-57-4/Gold Sodium Thiomalate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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