| Posthysteroscopic hyponatremia. | |
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MedLine Citation:
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PMID: 8172218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case of severe hyponatremia following hysteroscopic myomectomy for uterine fibroids. This new technique, which requires large volumes of irrigation solution (1.5% glycine in this case), is being more widely applied as an alternative to open surgery. Thus, nephrologists may expect to encounter such cases as the female counterpart to transurethral resection of prostate-associated hyponatremia. Analysis of the dynamic features of this case, in the context of recent knowledge of glycine metabolism, suggests that the early severe hyponatremia is partly spurious, reflecting an osmotic effect of glycine (which is initially restricted to the extracellular space). As glycine progressively enters cells and is metabolized, the later phase of hyponatremia more accurately reflects true hypo-osmolality. |
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Authors:
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R Gonzales; J M Brensilver; J J Rovinsky |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of kidney diseases : the official journal of the National Kidney Foundation Volume: 23 ISSN: 0272-6386 ISO Abbreviation: Am. J. Kidney Dis. Publication Date: 1994 May |
Date Detail:
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Created Date: 1994-05-27 Completed Date: 1994-05-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8110075 Medline TA: Am J Kidney Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 735-8 Citation Subset: IM |
Affiliation:
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Department of Medicine, New Rochelle Hospital Medical Center, NY. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Extracellular Space / metabolism Female Glycine / adverse effects, pharmacokinetics Humans Hyponatremia / etiology* Hysteroscopy / adverse effects* Intracellular Fluid / metabolism Osmolar Concentration |
| Chemical | |
Reg. No./Substance:
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56-40-6/Glycine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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