Document Detail


Posthumous sperm retrieval: analysis of time interval to harvest sperm.
MedLine Citation:
PMID:  16959804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Current recommendations regarding posthumous sperm retrieval (PSR) are based on a small number of cases. Our purpose was to determine the time interval from death to a successful procedure. METHODS: Seventeen consecutive PSR procedures in 14 deceased and 3 neurologically brain-dead patients at two male infertility centres [Sheba Medical Center (SMC), Tel-Hashomer, Israel and University of California San Francisco (UCSF), San Francisco, CA, USA] were analysed. Main outcome measures were retrieval of vital sperm, pregnancies and births. RESULTS: PSR methods included resection of testis and epididymis (n = 8), en-block excision of testis, epididymis and proximal vas deferens with vasal irrigation (n = 6), electroejaculation (EEJ) (n = 2) and epididymectomy (n = 1). PSR was performed 7.5-36 h after death. Sperm was retrieved in all cases and was motile in 14 cases. In two cases, testicular and epididymal tissues were cryopreserved without sperm evaluation, and in one case, no motility was detected. IVF and ICSI were performed in two cases in which sperm had been retrieved 30 h after death, and both resulted in pregnancies and live births. CONCLUSIONS: Viable sperm is obtainable with PSR well after the currently recommended 24-h time interval. PSR should be considered up to 36 h after death, following appropriate evaluation. No correlation was found between cause of death and chance for successful sperm retrieval.
Authors:
Shai Shefi; Gil Raviv; Michael L Eisenberg; Ruth Weissenberg; Liza Jalalian; Jacob Levron; Gili Band; Paul J Turek; Igael Madgar
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-09-07
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  21     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-12     Completed Date:  2007-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  2890-3     Citation Subset:  IM    
Affiliation:
Department of Urology, Chaim Sheba Medical Center, Tel-Hashomer, Israel. sshefi@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Cryopreservation
Death, Sudden
Female
Humans
Israel
Male
Marital Status
Patient Selection
Posthumous Conception / statistics & numerical data*
Postmortem Changes
Reproductive Techniques, Assisted
Retrospective Studies
Sperm Motility
Sperm Retrieval
Spermatozoa*
Time Factors
Tissue and Organ Harvesting / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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