Document Detail

Postexercise systolic time intervals in the midsystolic click syndrome.
MedLine Citation:
PMID:  872154     Owner:  NLM     Status:  MEDLINE    
Postexercise systolic time intervals (STI) were measured in ten patients (PMV group) with auscultatory evidence of the midsystolic click syndrome (i.e. one or more systolic nonejection clicks alone or in association with the late systolic murmur), and compared to eight age-matched volunteers (control group) with no evidence of heart disease. Following measurement of supine STIs, the subjects pedalled an upright bicycle ergometer at progressive work loads until a target heart rate (HR) representing 85% of the age-adjusted maximum was attained, or an abnormal end point was noted. Immediately postexercise, a repeat measurement of STIs, was obtained. A shortened or unchanged postexercise left ventricular ejection time corrected for HR (deltaLVETc) and a marked shortening of total electromechanical systole after exercise (deltaQS2c) constituted a normal STI response to stress testing and was noted in all control subjects. All of the PMV group exhibited evidence of left ventricular dysfunction characterized by a prolonged deltaLVETc. It is concluded that an abnormal STI response to exercise consistent with left ventricular dysfunction can be demonstrated in patients with prolapse of the mitral valve by the response of the STI.
A B Miller; R C Bahler
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  62     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1977  
Date Detail:
Created Date:  1977-08-12     Completed Date:  1977-08-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  44-50     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / physiopathology
Blood Pressure
Exercise Test*
Heart Auscultation*
Heart Rate
Heart Sounds*
Heart Ventricles / physiopathology
Middle Aged
Mitral Valve Insufficiency / diagnosis*,  physiopathology
Oxygen Consumption

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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