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Posterolateral versus posterior interbody fusion in isthmic spondylolisthesis.
MedLine Citation:
PMID:  22260338     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Spondylolisthesis is a heterogeneous disorder characterised by subluxation of a verte¬bral body over another in sagittal plane. Its most common form is isthmic spondylolisthesis (IS). This study aims to compare clinical outcomes of posterolateral fusion (PLF) with posterior instrumentation and posterior interbody fusion (PLIF) with posterior instrumentation in the treatment of IS. We performed a randomized prospective study in which 80 patients out of total of 85 patients with IS were randomly allocated to one of 2 groups: PLF with posterior instrumentation (group I) or PLIF with posterior instrumentation (group II). Posterior decompression was performed in the patients. The Oswestry low back pain disability (OLBP) scale and visual analogue scale (VAS) were used to evaluate the quality of life (QOL) and pain, respectively. The Fisher exact test was used to evaluate fusion rate and Mann-Whitney U-test was used to compare categorical data. Fusion in group II was significantly better than group I (P=0.012). Improvement in low back pain was statistically more significant in group I (P=0.001). Incidence of neurogenic claudication was significantly lower in group I than group II (P=0.004). In group I, there was no significant correlation between slip Meyerding grade and disc space height, radicular pain, and low back pain. There was no significant difference in postoperative complications at the 1-year follow-up period. Our data showed that PLF with posterior instrumentation provides better clinical outcomes and more improvement in low back pain compared to PLIF with posterior instrumentation despite low fusion rate. Key words: Clinical outcome, Fusion rate, Isthmic spondylolisthesis (IS), Posterior lumbar interbody fusion (PLIF), Posterolateral fusion (PLF).
Authors:
Majid Reza Farrokhi; Abdolkarim Rahmanian; Mohammad Sadegh Masoudi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-19
Journal Detail:
Title:  Journal of neurotrauma     Volume:  -     ISSN:  1557-9042     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8811626     Medline TA:  J Neurotrauma     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Associate Professor of Neurosurgery, Shiraz Neurosciences Research Center, Neurosurgery Department, Shiraz University of Medical Sciences, Shiraz, Iran., Shiraz, Iran, Islamic Republic of; farrokhimr@yahoo.com.
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