Document Detail

Posterior reversible encephalopathy syndrome: a report of a case with atypical features.
MedLine Citation:
PMID:  18717659     Owner:  NLM     Status:  MEDLINE    
We report a case of a young woman presenting with profound depression of consciousness and intra-uterine death in the late stages of an unbooked pregnancy. She proceeded to develop features of cardiovascular, renal, hepatic and haematological failures. The patient was challenging to manage in view of uncertainty regarding the underlying cause, and required multidisciplinary consultation. A diagnosis was subsequently made of posterior reversible encephalopathy syndrome in the context of pre-eclampsia. We review the typical presentation and wide-ranging associations of this recently described clinico-neuroradiological syndrome, and look at how appropriate management may lead to rapid resolution of its often life-threatening features. We highlight the importance to anaesthetists and critical care physicians of recognising even atypical cases such as this one in view of key differences in management from similarly presenting conditions.
J N Pratap; J F Down
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-08-19
Journal Detail:
Title:  Anaesthesia     Volume:  63     ISSN:  1365-2044     ISO Abbreviation:  Anaesthesia     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-26     Completed Date:  2008-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  1245-8     Citation Subset:  AIM; IM    
Department of Anaesthesia, University College Hospital, London, UK.
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MeSH Terms
Coma / etiology
Fetal Death / etiology
Magnetic Resonance Imaging
Posterior Leukoencephalopathy Syndrome / diagnosis*
Pre-Eclampsia / diagnosis
Pregnancy Complications / diagnosis*
Tomography, X-Ray Computed
Young Adult

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