| Posterior reversible encephalopathy syndrome in childhood: report of four cases and review of the literature. | |
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MedLine Citation:
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PMID: 22307182 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) is a recently described disorder with typical radiological findings of bilateral gray and white matter abnormalities in the posterior regions of the cerebral hemispheres and cerebellum. Its clinical symptoms include headache, decreased alertness, mental abnormalities such as confusion, diminished spontaneity of speech, and changed behavior ranging from drowsiness to stupor, seizures, vomiting, and abnormalities of visual perception such as cortical blindness. In this study, the clinical and radiological findings of 4 children with this syndrome due to a variety of conditions are reported. METHODS: The records of 4 children with a diagnosis of PRES were retrospectively analyzed. RESULTS: PRES is associated with a disorder of cerebrovascular autoregulation of multiple etiologies. Four patients with PRES who had primary diagnoses of severe aplastic anemia, nephritic syndrome, Henoch-Schönlein purpura, and acute poststreptococcal glomerulonephritis are presented. This syndrome has been described in numerous medical conditions, including hypertensive encephalopathy, eclampsia, and with the use of immunosuppressive drugs. CONCLUSIONS: Early recognition of PRES as a complication during different diseases and therapies in childhood may facilitate precise diagnosis and appropriate treatment. |
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Authors:
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Ayumi Endo; Tatsuo Fuchigami; Maki Hasegawa; Koji Hashimoto; Yukihiko Fujita; Yasuji Inamo; Hideo Mugishima |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatric emergency care Volume: 28 ISSN: 1535-1815 ISO Abbreviation: Pediatr Emerg Care Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-02-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8507560 Medline TA: Pediatr Emerg Care Country: United States |
Other Details:
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Languages: eng Pagination: 153-7 Citation Subset: IM |
Affiliation:
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From the *Department of Pediatrics and Child Health, Nihon University School of Medicine, Itabashi-ku; and †Department of General Pediatrics, Nihon University Nerima Hikarigaoka Hospital, Nihon University School of Medicine, Nerima-ku, Tokyo, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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