Document Detail


Posterior leukoencephalopathy and nephrotic syndrome: just a coincidence?
MedLine Citation:
PMID:  15090755     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Posterior leukoencephalopathy syndrome (PLES) is an acute neurological disorder. The most plausible hypothesis for the pathophysiology of PLES is the loss of autoregulation and consequent vasogenic edema. PLES is mostly attributed to severe or sudden elevations of arterial blood pressure. A number of reports, however, describe patients with PLES without severe hypertension. This report presents two patients with nephrotic syndrome who developed PLES without customarily severe hypertension. Proteinuria, low levels of serum albumin, or generalized increase in capillary permeability in nephrotic syndrome can initiate PLES with moderately high arterial blood pressure levels. PLES is increasingly recognized by neurologists, but it should also be remembered by internists when confronted with patients with nephrotic syndrome who present with neurological symptoms, whether or not they have severe hypertension.
Authors:
Duygu Yazgan Aksoy; Mustafa Arici; Ahmet Alper Kiykim; Mine Durusu; Gurdal Sahin; Dilek Ertoy Baydar; Bulent Altun; Yunus Erdem; Unal Yasavul; Cetin Turgan; Sali Caglar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  327     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-04-19     Completed Date:  2004-05-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  156-9     Citation Subset:  AIM; IM    
Affiliation:
Departments of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey. dcemaksoy@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Diseases / etiology*
Female
Humans
Hypertension / complications
Middle Aged
Nephrotic Syndrome / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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