Document Detail

Posterior chamber injection of intracameral mydriatics increases the durability of the mydriatic response.
MedLine Citation:
PMID:  22963348     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare the mydriatic effect of intracameral mydriatics injected into the anterior or the posterior chamber in routine phacoemulsification cataract surgery.
METHODS: Forty-four patients planned for unilateral phacoemulsification surgery were included after informed consent. Mydriasis was achieved by injecting 150 μl of a mixture of phenylephrine 1.5% and lidocaine 1.0% at the beginning of the procedure. The patients were randomly assigned to injection into the anterior or the posterior chamber. The pupils were filmed during the procedures, and the mean pupil diameters were measured at predetermined intervals from the video recordings by an independent observer.
RESULTS: Immediately after the injection, the pupils were larger after posterior chamber injection (3.8 ± 0.8 versus 3.1 ± 0.7 mm; p = 0.004). A similar difference was seen after the phacoemulsification (6.4 ± 0.7 versus 5.9 ± 1.0 mm; p = 0.031). The mydriatic durability was also better after posterior injection (p = 0.004-0.041).
CONCLUSIONS: Apart from immediately after the injection, the initial mydriatic response was similar with both injection techniques, but the durability of the mydriasis was slightly better after a posterior chamber injection of ICM.
Oscar Lundqvist; Anders Behndig
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2012-09-11
Journal Detail:
Title:  Acta ophthalmologica     Volume:  91     ISSN:  1755-3768     ISO Abbreviation:  Acta Ophthalmol     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-10-17     Completed Date:  2014-04-23     Revised Date:  2014-05-29    
Medline Journal Info:
Nlm Unique ID:  101468102     Medline TA:  Acta Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  657-9     Citation Subset:  IM    
Copyright Information:
© 2012 The Authors. Acta Ophthalmologica © 2012 Acta Ophthalmologica Scandinavica Foundation.
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MeSH Terms
Anterior Chamber / drug effects
Drug Combinations
Injections, Intraocular / methods*
Lens Implantation, Intraocular
Lidocaine / administration & dosage
Mydriatics / administration & dosage*
Phenylephrine / administration & dosage
Pupil / drug effects*
Reg. No./Substance:
0/Drug Combinations; 0/Mydriatics; 1WS297W6MV/Phenylephrine; 98PI200987/Lidocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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