| Posterior Reversible Encephalopathy Syndrome (PRES) With Immune System Activation, VEGF Up-Regulation, and Cerebral Amyloid Angiopathy. | |
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MedLine Citation:
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PMID: 21150450 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The case of a 75-year-old man with a history of lymphoma, recent upper respiratory tract infection, and a protracted course of encephalopathy is presented. Radiologically, findings were consistent with posterior reversible encephalopathy syndrome. A brain biopsy revealed evidence of endothelial activation, T-cell trafficking, and vascular endothelial growth factor expression, suggesting that systemic immune system activation may be involved with triggering posterior reversible encephalopathy syndrome. In addition, underlying cerebral amyloid angiopathy may have contributed to the initial nonclassical edema distribution by compromising autoregulatory blood flow mechanisms. |
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Authors:
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Julia Kofler; Walter S Bartynski; Thomas Q Reynolds; Frank S Lieberman; Geoffrey H Murdoch; Ronald L Hamilton |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 35 ISSN: 1532-3145 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2011 Jan-Feb |
Date Detail:
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Created Date: 2011-01-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 39-42 Citation Subset: IM |
Affiliation:
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From the *Departments of Pathology, †Radiology, and ‡Neurology, University of Pittsburgh, Pittsburgh, PA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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