| Posterior Reversible Encephalopathy Syndrome (PRES) in 5-year-old girl with nephrotic syndrome. | |
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MedLine Citation:
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PMID: 20588234 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Posterior Reversible Encephalopathy Syndrome (PRES) is a rare complication of nephrotic syndrome in children. This clinical condition is caused by localized brain angioedema mostly in parieto-occipital region and results in dramatic and acute features as sudden loss of consciousness, epileptic paroxysms, strong headache or visual disturbances. Uncontrolled hypertension often participates in PRES development. CASE: We present the case of a 5-year-old girl treated for relapse of nephrotic syndrome. RESULTS: At the time of edema regression and weight reduction, a sudden loss of consciousness and worsening of hypertension occurred. Brain MRI demonstrated extended multifocal changes strongly suspicious of encephalitis. After exclusion of herpetic encephalitis, the clinical picture was classified as PRES. Successful antihypertensive treatment led to general improvement of the girl's health within 48 hours and resolution of MRI brain hyperintensities occurred within the next three months. CONCLUSIONS: The aim of our case report is to us remind of possible development of PRES at the time of edema regression in nephrotic syndrome. |
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Authors:
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Pavel Kabicek; Stepan Sulek; Zdenek Seidl; Manuela Vaneckova; Edita Kabickova; Vaclav Vobruba; Laszlo Wenchich; Jiri Zeman |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuro endocrinology letters Volume: 31 ISSN: 0172-780X ISO Abbreviation: Neuro Endocrinol. Lett. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-23 Completed Date: 2010-10-08 Revised Date: 2011-02-07 |
Medline Journal Info:
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Nlm Unique ID: 8008373 Medline TA: Neuro Endocrinol Lett Country: Sweden |
Other Details:
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Languages: eng Pagination: 297-300 Citation Subset: IM |
Affiliation:
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Department of Pediatrics and Adolescent Medicine, General University Hospital and 1st Faculty of Medicine, Charles University Prague, Czech Republic. p.kabicek@post.cz |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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therapeutic use Child Female Humans Magnetic Resonance Imaging Nephrotic Syndrome / complications*, drug therapy Posterior Leukoencephalopathy Syndrome / complications* |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
| Comments/Corrections | |
Comment In:
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Neuro Endocrinol Lett. 2010;31(6):728; author reply 729-30
[PMID:
21196919
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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