Document Detail


Postcoital contraception underrecognized and underutilized.
MedLine Citation:
PMID:  12287765     Owner:  PIP     Status:  MEDLINE    
Abstract/OtherAbstract:
Postcoital contraception can play an important role in the prevention of unwanted adolescent pregnancy in the US. Diethylstilbestrol (DES), 25 mg twice daily for 5 days within 24 to a maximum of 72 hours after unprotected sexual intercourse, received US Food and Drug Administration (FDA) approval for pregnancy prevention in 1973. In 1978, however, the manufacturer, Eli Lilly, included in its packaging instructions that DES should not be used for postcoital contraception given the development of clear-cell adenocarcinoma of the vagina or cervix in the daughters of women who took DES to prevent spontaneous abortion. The FDA had not withdrawn its approval of DES for this purpose. Other drugs that have been effectively used for postcoital contraception include 0.5 mg of norgestrel and 0.05 mg of ethinyl estradiol (2 tablets within 72 hours of unprotected intercourse and another 2 tablets 12 hours later) and conjugated estrogens. This approach to pregnancy prevention sidesteps many of the medical and moral complexities associated with use of the abortifacient RU-486. In fact, the Catholic bishops of Great Britain have approved the use of postcoital contraception in women who are victims of sexual assault.
Authors:
J J Demarco
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Female patient     Volume:  17     ISSN:  0364-1198     ISO Abbreviation:  Female Patient     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1994-12-01     Completed Date:  1994-12-01     Revised Date:  2012-02-15    
Medline Journal Info:
Nlm Unique ID:  7802840     Medline TA:  Female Patient     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  24, 26     Citation Subset:  J    
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MeSH Terms
Descriptor/Qualifier:
Americas
Biology
Catholicism*
Christianity
Contraception
Contraceptive Agents
Contraceptive Agents, Female
Contraceptives, Postcoital*
Crime
Demography
Developed Countries
Diethylstilbestrol*
Endocrine System
Estrogens
Family Planning Services
Fertility
Hormones
North America
Physiology
Population
Population Dynamics
Pregnancy in Adolescence*
Rape*
Religion
Sexual Behavior
Social Problems
United States
Chemical
Reg. No./Substance:
0/Contraceptive Agents; 0/Contraceptive Agents, Female; 0/Contraceptives, Postcoital; 0/Estrogens; 0/Hormones; 56-53-1/Diethylstilbestrol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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