Document Detail


Postantibiotic effect of ceftobiprole against 12 Gram-positive organisms.
MedLine Citation:
PMID:  17065631     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The in vitro postantibiotic effects (PAEs), postantibiotic sub-MIC effects (PA-SMEs), and sub-MIC effects of ceftobiprole were determined for 12 gram-positive organisms. Pneumococcal, staphylococcal, and enterococcal PAEs were 1.4 to 3.1 h, 0 to 1.8 h, and 0 to 0.9 h, respectively. The PA-SMEs (0.4 times the MIC) for pneumococci, staphylococci, and enterococci were 4.8 to >10.3 h, 1.5 to 9.6 h, and 3.8 to >10.7 h, respectively.
Authors:
G A Pankuch; P C Appelbaum
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  50     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-26     Completed Date:  2006-12-11     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3956-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, Hershey Medical Center, P.O. Box 850, Hershey, PA 17033, USA. pappelbaum@psu.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / pharmacology*
Cephalosporins / pharmacology*
Enterococcus faecalis / drug effects
Gram-Positive Bacteria / drug effects*
Humans
Microbial Sensitivity Tests
Staphylococcus aureus / drug effects
Streptococcus pneumoniae / drug effects
beta-Lactams / pharmacology
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Cephalosporins; 0/beta-Lactams; 5T97333YZK/ceftobiprole
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of various media on the activity of NXL103 (formerly XRP 2868), a new oral streptogramin, ag...
Next Document:  Survival of patients with stage I lung cancer detected on CT screening.