| Post-traumatic-shock lung: postmortem microangiographic and pathologic correlation. | |
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MedLine Citation:
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PMID: 6981307 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In post-traumatic-shock lung, increased pulmonary vascular resistance and pulmonary hypertension are prominent features. The explanation for them was sought by postmortem microangiography of the lungs of 17 patients dying of respiratory failure after trauma. The 10 patients with thoracic injury died earlier (1-8 days). Extravasation of contrast material due to alveolar capillary rupture was present in all but one specimen and occupied 20% of the sampled area. Pulmonary artery thrombi lay proximal to these extravasations. Hypovascular areas due to infection and hemorrhagic alveolitis were found in all patients and involved 40% of the surface area. The small pulmonary arteries were poorly filled and contained many microthrombi. Some patients had hematomas, cavities, and areas of interstitial edema occupying about 5% of the lung area and associated with compressed or occluded vessels. Several mechanisms including pulmonary trauma may be responsible for the antemortem rupture and obstruction of small blood vessels. In the post-traumatic-shock lung, small artery occlusion and compression are associated with pulmonary hemorrhage, infarction, and infection and are important contributors to perfusion abnormalities and respiratory failure. |
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Authors:
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F Pinet; A Tabib; A Clermont; R Loire; J Motin; F Artru |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 139 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 1982 Sep |
Date Detail:
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Created Date: 1982-10-12 Completed Date: 1982-10-12 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 449-54 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Angiography / methods* Child Extravasation of Diagnostic and Therapeutic Materials Female Humans Lung / blood supply*, pathology Male Middle Aged Respiratory Distress Syndrome, Adult / pathology, radiography* |
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