| Post-thrombotic syndrome after total hip arthroplasty is uncommon. | |
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MedLine Citation:
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PMID: 19085497 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Deep vein thrombosis (DVT), usually asymptomatic, is common after total hip arthroplasty (THA). Post-thrombotic syndrome (PTS) is a potential late complication of DVT, but there is limited data on its occurrence. PATIENTS AND METHODS: This was a prospective cohort study of subjects at one hospital who had participated in a trial of thromboprophylaxis for THA and who had postoperative venography. Data were collected at baseline and 2-4 years later to ascertain symptoms of PTS using a modification of a validated scoring system. Outcomes were collected without knowledge of baseline characteristics or venogram results. Potential predictors of PTS were explored using exact logistic regression analyses. RESULTS: The cohort (n=188) had a mean age of 63 years, 51% were male, 35% had a BMI of>30, and 4% had a prior history of DVT. 25 patients (13%) had DVTs on venography. 12 patients (6%, 95% CI: 3-11) subsequently developed symptoms consistent with PTS, 7 with bilateral symptoms. Most affected limbs (15 of 19) had no postoperative DVT. No statistically significant predictors of PTS were found. INTERPRETATION: Symptoms of PTS are infrequent after THA in patients who receive some form of thromboprophylaxis. Our findings, which are consistent with the existing literature, suggest that there is a potential benefit to giving thromboprophylaxis for reduction of symptomatic PTS. |
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Authors:
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Michael J Mant; Dean T Eurich; Donald B Russell; Sumit R Majumdar |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Acta orthopaedica Volume: 79 ISSN: 1745-3682 ISO Abbreviation: Acta Orthop Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-12-16 Completed Date: 2009-01-09 Revised Date: 2009-12-11 |
Medline Journal Info:
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Nlm Unique ID: 101231512 Medline TA: Acta Orthop Country: Sweden |
Other Details:
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Languages: eng Pagination: 794-9 Citation Subset: IM |
Affiliation:
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Department of Medicine, Division of Hematology and Oncology, University of Alberta, Edmonton, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arthroplasty, Replacement, Hip / adverse effects* Cohort Studies Female Humans Male Middle Aged Postoperative Complications / etiology, prevention & control, radiography Postphlebitic Syndrome / etiology*, prevention & control, radiography Prospective Studies Venous Thrombosis / etiology*, prevention & control, radiography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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