| Post-processing of dynamic gadolinium-enhanced magnetic resonance imaging exams of the liver: explanation and potential clinical applications for color-coded qualitative and quantitative analysis. | |
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MedLine Citation:
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PMID: 18210307 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this article is to explain and illustrate the current status and potential applications of automated and color-coded post-processing techniques for the analysis of dynamic multiphasic gadolinium-enhanced magnetic resonance imaging (MRI) of the liver. Post-processing of these images on dedicated workstations allows the generation of time-intensity curves (TIC) as well as color-coded images, which provides useful information on (neo)-angiogenesis within a liver lesion, if necessary combined with information on enhancement patterns of the surrounding liver parenchyma. Analysis of TIC and color-coded images, which are based on pharmacokinetic modeling, provides an easy-to-interpret schematic presentation of tumor behavior, providing additional characteristics for adequate differential diagnosis. Inclusion of TIC and color-coded images as part of the routine abdominal MRI workup protocol may help to further improve the specificity of MRI findings, but needs to be validated in clinical decision-making situations. In addition, these tools may facilitate the diagnostic workup of disease for detection, characterization, staging, and monitoring of antitumor therapy, and hold incremental value to the widely used tumor response criteria. |
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Authors:
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L Wang; I C Van den Bos; S M Hussain; P M Pattynama; M W Vogel; G P Krestin |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 49 ISSN: 1600-0455 ISO Abbreviation: Acta Radiol Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-01-22 Completed Date: 2008-03-04 Revised Date: 2008-03-25 |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: Sweden |
Other Details:
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Languages: eng Pagination: 6-18 Citation Subset: IM |
Affiliation:
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Department of Radiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands. wang6@mskcc.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Color Contrast Media / administration & dosage* Female Gadolinium / diagnostic use* Humans Image Enhancement / methods* Image Processing, Computer-Assisted / methods* Liver / pathology Liver Diseases / diagnosis* Liver Neoplasms / diagnosis* Magnetic Resonance Imaging / methods* Male Middle Aged Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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