Document Detail

Post-partum sacral fracture associated with heparin treatment.
MedLine Citation:
PMID:  18458990     Owner:  NLM     Status:  MEDLINE    
We report the case of a 19-year-old woman who consulted for low-back pain 3 weeks after her first delivery. This young woman had a personal history of protein C deficiency and was treated daily during her pregnancy with low-molecular-weight heparin. Her body mass index was 34 and she only gained 10 kg during her pregnancy. Since the delivery - which occurred without any complication - she had suffered from a gradually increasing right-buttock pain and limp. Magnetic resonance imaging (MRI) revealed a fracture of the right sacral ala. After analgesia and 1 month of home relative bed rest, the patient recovered her functional capacities. Regarding our patient, who had no potential clinical risk factors for osteoporosis, the causal effect of heparin is thus possible but not certain. This case report illustrates the fact that clinicians should have a high suspicion of pelvic fracture in post-partum women, even in very young ones, presenting sudden onset of low back and pelvic pain, especially when they have received heparin during pregnancy. MRI seems to be the key exam because it is able to detect and stage fractures or microfractures.
Vincent Goëb; Victor Strotz; Mathieu Verdet; Xavier Le Loët; Olivier Vittecoq
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-05-06
Journal Detail:
Title:  Clinical rheumatology     Volume:  27 Suppl 2     ISSN:  1434-9949     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-10     Completed Date:  2009-03-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  S51-3     Citation Subset:  IM    
Department of Rheumatology, Rouen University Hospital & Inserm U905 (IFRMP 23), Institute for Biomedical Research, University of Rouen, 76031 Rouen cedex, France.
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MeSH Terms
Heparin, Low-Molecular-Weight / adverse effects*,  therapeutic use
Low Back Pain / diagnosis,  etiology*
Magnetic Resonance Imaging
Postpartum Period
Pregnancy Complications* / drug therapy
Protein C Deficiency / drug therapy*
Sacrum / injuries*
Spinal Fractures / diagnosis,  etiology*
Young Adult
Reg. No./Substance:
0/Heparin, Low-Molecular-Weight

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