Document Detail

Post-myocardial infarction hormone therapy revisited.
MedLine Citation:
PMID:  22640475     Owner:  NLM     Status:  Publisher    
Current guidelines recommend that postmenopausal hormone therapy should not be used in the setting of secondary prevention of coronary heart disease, and that it should be stopped when an acute coronary event occurs. Reviewing the available data on the issue of discontinuation of therapy in post-myocardial infarction patients shows that the basis for this recommendation is not so solid and clear-cut. In fact, the few relevant studies concluded that cessation of hormone therapy carried no benefit, and perhaps even caused some adverse cardiac events, when compared to women who continued with treatment after they suffered a coronary event. The following article uses a recently published study as an opportunity to review this topic. Based on the literature, my personal view is that long-term hormone users should not automatically withhold therapy post-myocardial infarction, but careful individual evaluation and consideration should precede any decision.
A Pines
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-28
Journal Detail:
Title:  Climacteric : the journal of the International Menopause Society     Volume:  -     ISSN:  1473-0804     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9810959     Medline TA:  Climacteric     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Medicine 'T' , Ichilov Hospital, Tel-Aviv , Israel.
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