Document Detail


Post-mortem MRI in newborns when autopsy is not permitted
MedLine Citation:
PMID:  18590065     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
2 newborns, boys weighing 1400 and 950 g, died 2 and 8 hours after birth respectively. Autopsy was not permitted but MRI was possible. In the first newborn, characteristic abnormalities ofa Potter's sequence were found: pulmonary hypoplasia, missing kidneys and ureters and a rudimentary bladder. Clinically, a small chest, low-positioned ears, a flattened nose, a retracted chin, contractures of both knees and a talipes equinus of both feet had already been observed. In the second newborn, an MRI scan of the skull revealed a torn cerebellar tentorium with intracranial bleeding. The cause of death in newborns is often unknown. Autopsy is the gold standard for determining the cause of death. However for a variety of reasons, many parents do not give informed consent for autopsy. In such cases, post-mortem MRI may be an alternative. Abnormalities ofthe central nervous system, muscles and internal organs can usually be clearly visualized using MRI. However, the diagnosis of cardiac abnormalities using this technique is more difficult.
Authors:
K G J A Voogdt; R J Vermeulen; J I M L Verbeke; L C D Wijnaendts; R M van Elburg
Publication Detail:
Type:  Case Reports; English Abstract; Journal Article    
Journal Detail:
Title:  Nederlands tijdschrift voor geneeskunde     Volume:  152     ISSN:  0028-2162     ISO Abbreviation:  Ned Tijdschr Geneeskd     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-07-01     Completed Date:  2008-07-29     Revised Date:  2008-08-27    
Medline Journal Info:
Nlm Unique ID:  0400770     Medline TA:  Ned Tijdschr Geneeskd     Country:  Netherlands    
Other Details:
Languages:  dut     Pagination:  1287-91     Citation Subset:  IM    
Affiliation:
Afd. Kindergeneeskunde, VU Medisch Centrum, Postbus 7057, 1007 MB Amsterdam.
Vernacular Title:
MRI post mortem bij pasgeborenen bij wie obductie niet wordt toegestaan.
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MeSH Terms
Descriptor/Qualifier:
Autopsy
Cause of Death*
Diagnosis, Differential
Humans
Infant, Newborn*
Magnetic Resonance Imaging / methods*
Male
Comments/Corrections
Comment In:
Ned Tijdschr Geneeskd. 2008 Aug 2;152(31):1749; author reply 1749-50   [PMID:  18727608 ]
Erratum In:
Ned Tijdschr Geneeskd. 2008 Aug 2;152(31):1752

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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