Document Detail


Post-mortem High-field magnetic resonance imaging: effect or various factors.
MedLine Citation:
PMID:  23339743     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Purpose: To evaluate image quality and diagnostic accuracy of High-field post-mortem (PM) magnetic resonance imaging(MRI) on fetuses below 20 weeks of gestation before and after the freeze-thaw process. Materials and Methods: Nine fetuses were scanned with 3 different scanning procedures: "fresh", just after termination of pregnancy(TOP), "non-fresh short scan" and "non-fresh long scan" after being kept at -20 °C, followed by conventional autopsy. The brain, thorax except the heart, heart and abdomen were studied. The qualities of the images for the 4 different fetal regions and for the 3 different scanning procedures were reported. Regression analysis was used to investigate the effect on image quality of different factors. Additionally, the diagnostic accuracy was also evaluated. Results: Fetuses at 12.0-19.6 weeks were included. Regression analysis showed that better image quality was correlated to advanced gestation at TOP and scan on fresh fetuses. PM-MRI on fresh fetuses was always diagnostic for the brain and in more than half of cases on non-fresh fetuses and was nearly equally diagnostic for thoracic and abdominal structures. Conclusion: High-field PM-MRI seems to offer a quite reliable alternative to parents declining conventional PM for fetuses before 20 weeks whether these fetuses are freshly scanned or after being frozen.
Authors:
Marleen Verhoye; Carmela Votino; Mieke M Cannie; Valérie Segers; Chiara Mabiglia; Teresa Cos; Dominique Lipombi; Jacques C Jani
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-23
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
University of Antwerp, Antwerp, Bio-Imaging Lab, Belgium, departments of Obstetrics and Gynaecology.
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