| Post kala-azar ocular leishmaniasis. | |
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MedLine Citation:
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PMID: 9764325 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinical features, diagnosis and treatment of 6 patients with post kala-azar ocular leishmaniasis are described. The eye lesions were associated with past or concomitant post kala-azar dermal leishmaniasis (PKDL). Four patients had post kala-azar leishmanial conjunctivitis and blepharitis. Using the polymerase chain reaction, the causative parasite was characterized as Leishmania donovani in 2 of these 4 patients. Two patients had post kala-azar anterior uveitis. The diagnosis of uveitis was based on the clinical manifestations, temporal relation to treated visceral leishmaniasis, the association with PKDL and positive anti-Leishmania serology. All patients were treated with systemic sodium stibogluconate. Patients with anterior uveitis were also treated with steroid and atropine eyedrops. The response to treatment was good. The importance of early diagnosis and treatment of ocular leishmaniasis is stressed. |
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Authors:
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A M el Hassan; E A Khalil; E A el Sheikh; E E Zijlstra; A Osman; M E Ibrahim |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Transactions of the Royal Society of Tropical Medicine and Hygiene Volume: 92 ISSN: 0035-9203 ISO Abbreviation: Trans. R. Soc. Trop. Med. Hyg. Publication Date: 1998 Mar-Apr |
Date Detail:
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Created Date: 1998-10-26 Completed Date: 1998-10-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7506129 Medline TA: Trans R Soc Trop Med Hyg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 177-9 Citation Subset: IM |
Affiliation:
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Institute of Endemic Diseases, University of Khartoum, Sudan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Antimony Sodium Gluconate / therapeutic use Antiprotozoal Agents / therapeutic use Atropine / therapeutic use Blepharitis / drug therapy, parasitology Child Conjunctivitis / drug therapy, parasitology Eye Infections, Parasitic / complications*, diagnosis, drug therapy Female Humans Leishmaniasis, Visceral / complications*, diagnosis, drug therapy Male Middle Aged Mydriatics / therapeutic use Ophthalmic Solutions Steroids / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antimony Sodium Gluconate; 0/Antiprotozoal Agents; 0/Mydriatics; 0/Ophthalmic Solutions; 0/Steroids; 51-55-8/Atropine |
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