Document Detail


Post kala-azar ocular leishmaniasis.
MedLine Citation:
PMID:  9764325     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The clinical features, diagnosis and treatment of 6 patients with post kala-azar ocular leishmaniasis are described. The eye lesions were associated with past or concomitant post kala-azar dermal leishmaniasis (PKDL). Four patients had post kala-azar leishmanial conjunctivitis and blepharitis. Using the polymerase chain reaction, the causative parasite was characterized as Leishmania donovani in 2 of these 4 patients. Two patients had post kala-azar anterior uveitis. The diagnosis of uveitis was based on the clinical manifestations, temporal relation to treated visceral leishmaniasis, the association with PKDL and positive anti-Leishmania serology. All patients were treated with systemic sodium stibogluconate. Patients with anterior uveitis were also treated with steroid and atropine eyedrops. The response to treatment was good. The importance of early diagnosis and treatment of ocular leishmaniasis is stressed.
Authors:
A M el Hassan; E A Khalil; E A el Sheikh; E E Zijlstra; A Osman; M E Ibrahim
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transactions of the Royal Society of Tropical Medicine and Hygiene     Volume:  92     ISSN:  0035-9203     ISO Abbreviation:  Trans. R. Soc. Trop. Med. Hyg.     Publication Date:    1998 Mar-Apr
Date Detail:
Created Date:  1998-10-26     Completed Date:  1998-10-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7506129     Medline TA:  Trans R Soc Trop Med Hyg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  177-9     Citation Subset:  IM    
Affiliation:
Institute of Endemic Diseases, University of Khartoum, Sudan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Antimony Sodium Gluconate / therapeutic use
Antiprotozoal Agents / therapeutic use
Atropine / therapeutic use
Blepharitis / drug therapy,  parasitology
Child
Conjunctivitis / drug therapy,  parasitology
Eye Infections, Parasitic / complications*,  diagnosis,  drug therapy
Female
Humans
Leishmaniasis, Visceral / complications*,  diagnosis,  drug therapy
Male
Middle Aged
Mydriatics / therapeutic use
Ophthalmic Solutions
Steroids / therapeutic use
Chemical
Reg. No./Substance:
0/Antimony Sodium Gluconate; 0/Antiprotozoal Agents; 0/Mydriatics; 0/Ophthalmic Solutions; 0/Steroids; 51-55-8/Atropine

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