| Post-kala-azar dermal leishmaniasis: a clinical and therapeutic study. | |
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MedLine Citation:
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PMID: 8387467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Post-kala-azar dermal leishmaniasis is a condition peculiarly confined to the Indian subcontinent. METHODS: The clinical features and investigations in 18 patients of post-kala-azar dermal leishmaniasis were studied. RESULTS: There was a polymorphic picture from hypopigmented macules to nodules and plaques. Mucous membranes were affected in five, the lips and glans penis being the most frequent sites. Histopathologically, a rich dermal infiltrate was seen in indurated lesions and in macules; it was confined to perivascular foci in the upper dermis. Leishman-Donovan bodies were seen in 16. CONCLUSIONS: The lesions cleared in 4 to 5 months after treatment with sodium antimony gluconate intramuscularly 20 mg/kg/day up to a maximum of 1 g/day. The drug was well tolerated. |
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Authors:
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V Ramesh; R S Misra; U Saxena; A Mukherjee |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of dermatology Volume: 32 ISSN: 0011-9059 ISO Abbreviation: Int. J. Dermatol. Publication Date: 1993 Apr |
Date Detail:
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Created Date: 1993-06-08 Completed Date: 1993-06-08 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 0243704 Medline TA: Int J Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 272-5 Citation Subset: IM |
Affiliation:
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Department of Dermatology and Leprology, Safdarjang Hospital, New Delhi, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Antimony Sodium Gluconate / therapeutic use* Biopsy Child Diagnostic Tests, Routine Female Follow-Up Studies Humans Leishmaniasis, Cutaneous* / diagnosis, drug therapy, etiology Leishmaniasis, Visceral / complications* Male Middle Aged Skin / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Antimony Sodium Gluconate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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