Document Detail

Post-interval syndrome after carbon monoxide poisoning.
MedLine Citation:
PMID:  15303387     Owner:  NLM     Status:  MEDLINE    
Carbon monoxide (CO) exposure and toxicity is a potentially lethal disorder with immediate and delayed side effects. A 24-y-old driver was admitted to the University-based emergency department with altered mental status. He was found unconscious in the driver's seat of his vehicle in an indoor garage the morning before. An estimated 7 h later, he was comatose and taken to a nearby village clinic. Oxygen was administered immediately. Later, he was transferred to the university hospital. At the 12th h after exposure, the Glasgow Coma Scale score was 12/15 (E3, M5, V4). Co-oximetry disclosed a carboxyhemoglobin concentration of 10.5%. Normobaric oxygen was administered. He recovered completely the 3rd d after exposure; however, on the 7th d disorientation and agitation was noted, and the interval form of CO poisoning and leukoencephelopaty were suspected, for which he was readmitted the 10th d after exposure. Analysis of cerebrospinal fluid and blood revealed no abnormalities. Magnetic resonance imaging on the 11th d after exposure demonstrated an ischemic area in the posterior temporoparietal area. The patient continued improvement to discharge at 7th d of the second admission. Close follow-up should be scheduled for CO-poisoned patients to rule out the post-interval syndrome for at least 1 mo. This should also include those with apparent clinical and laboratory recovery.
Sahin Aslan; Ozgur Karcioglu; Fatih Bilge; Mehmet Meral; Zulal Ozkurt; Mustafa Uzkeser
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Veterinary and human toxicology     Volume:  46     ISSN:  0145-6296     ISO Abbreviation:  Vet Hum Toxicol     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-11     Completed Date:  2004-09-10     Revised Date:  2006-08-08    
Medline Journal Info:
Nlm Unique ID:  7704194     Medline TA:  Vet Hum Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  183-5     Citation Subset:  IM    
Department of Emergency Medicine, Ataturk University, School of Medicine, Erzurum, Turkey.
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MeSH Terms
Carbon Monoxide Poisoning / complications,  diagnosis*,  pathology
Diagnosis, Differential
Emergency Treatment
Glasgow Coma Scale
Hypoxia, Brain / etiology*,  pathology
Magnetic Resonance Imaging
Oxygen Inhalation Therapy
Unconsciousness / etiology,  pathology

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