Document Detail

Post-cholecystectomy pulmonary function following interpleural bupivacaine and intramuscular pethidine.
MedLine Citation:
PMID:  2596678     Owner:  NLM     Status:  MEDLINE    
Twenty-four patients who were to undergo cholecystectomy were randomised into two groups, one to receive postoperative analgesia with interpleural bupivacaine, 20 ml of a 0.5% solution with adrenaline 5 micrograms/ml, and the other to receive intramuscular pethidine, 1 mg/kg. Preoperative and postoperative pulmonary function, postoperative pain scores, and days from operation to hospital discharge were recorded and statistically compared. There was no significant difference in pain scores, nor in days to discharge; however, postoperative pulmonary mechanics were significantly poorer in the interpleural group. A hypothesis to explain the differences is offered.
D C Oxorn; G S Whatley
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  17     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-01-12     Completed Date:  1990-01-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  440-3     Citation Subset:  IM    
Department of Anaesthesia and Surgical Intensive Care, Halifax Infirmary, Nova Scotia.
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MeSH Terms
Anesthesia, General*
Bupivacaine / administration & dosage*
Forced Expiratory Volume / drug effects
Injections, Intramuscular
Lung Volume Measurements*
Meperidine / administration & dosage*
Middle Aged
Pain, Postoperative / drug therapy*
Pleura / drug effects
Vital Capacity / drug effects
Reg. No./Substance:
2180-92-9/Bupivacaine; 57-42-1/Meperidine
Comment In:
Anaesth Intensive Care. 1990 May;18(2):271-2   [PMID:  2368910 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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