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Post-cardiac arrest syndrome: Second thoughts regarding therapeutic hypothermia.
MedLine Citation:
PMID:  23057649     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
To the Editor: We have read with great interest the excellent article by Wold et al. which has been published in the latest issue of Acta Physiologica (Wold et al. 2012). The authors concluded that the cardiac contractile dysfunction after rewarming is explained not only by the aggravation of calcium overload during deep hypothermia (15 °C), but, also, by the decreased recovery of calcium homeostasis during rewarming. Although there is evidence that calcium ion concentration increases considerably after deep hypothermia and rewarming in animals with intact heart in a non-arrested state (Fedorov et al. 2005, Wold et al. 2012), mild therapeutic post-resuscitation hypothermia (32-34 °C) shares similar characteristics that may be of particular importance. © 2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society.
Authors:
Athanasios Chalkias; Theodoros Xanthos
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-12
Journal Detail:
Title:  Acta physiologica (Oxford, England)     Volume:  -     ISSN:  1748-1716     ISO Abbreviation:  Acta Physiol (Oxf)     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101262545     Medline TA:  Acta Physiol (Oxf)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society.
Affiliation:
National and Kapodistrian University of Athens, Medical School, Department of Anatomy, Athens, Greece.
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