Document Detail


Possible role of endothelium in the orientation of smooth muscle cells in experimental neointima.
MedLine Citation:
PMID:  3984668     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myointimal cells (MIC) orientation and intimal thickening evolution, induced by grafting an autogenous venous patch onto the rat common carotid artery, were studied with light microscopy at different times until 14 months after surgery. Intimal thickenings in the venous patch were most prominent at an intermediate postoperative period, after which their mean size did not change significantly. In host artery neointima, the greatest MIC proliferation was observed at a late stage of evolution. MIC arrangement was predominantly circumferential to the blood stream in venous patch neointima, whereas it was mostly axial in the host artery. The interaction between MIC orientation and endothelial regeneration in the operated vessel is discussed.
Authors:
D Reimers; J A Gutierrez Diaz; P Cuevas; M Dujovny; F G Diaz; J I Ausman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anatomica     Volume:  121     ISSN:  0001-5180     ISO Abbreviation:  Acta Anat (Basel)     Publication Date:  1985  
Date Detail:
Created Date:  1985-04-26     Completed Date:  1985-04-26     Revised Date:  2007-07-02    
Medline Journal Info:
Nlm Unique ID:  0370272     Medline TA:  Acta Anat (Basel)     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  140-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carotid Arteries
Endothelium / cytology,  physiology*
Microscopy, Electron
Muscle, Smooth, Vascular / cytology*,  transplantation
Rats
Rats, Inbred Strains
Saphenous Vein / transplantation
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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